Integrating AI in Therapeutic Hypothermia for Comatose Post Cardiac Arrest: A Review

Retnaningsih -, Abdulloh Machin, Mursyid Bustami, Riki Sukiandra, Alfansuri Kadri, Ramdinal Aviesena Zairinal, Sobaryati -, Baarid Luqman Hamidi, I Wayan Widyantara, Hendry Gunawan, Ary Setijadi, Agus Budiyono, Yandoko -, Rifky Ismail

Abstract


Therapeutic hypothermia and targeted temperature management have shown promise in improving outcomes for post-cardiac arrest patients. This review provides a comprehensive analysis of the current literature on these interventions. Key findings reveal their significant benefits in reducing neurological damage, improving survival rates, and enhancing long-term neurological outcomes. Optimal temperature ranges, cooling methods, and duration of cooling are discussed, along with challenges and complications. The role of advanced monitoring techniques and emerging technologies is examined. Standardized protocols and guidelines are emphasized to ensure consistent implementation. Future research directions include integrating artificial intelligence algorithms and advancements in cooling technologies. Overall, therapeutic hypothermia and targeted temperature management offer valuable interventions for enhancing post-cardiac arrest patient outcomes.

Keywords


therapeutic hypothermia, targeted temperature management, post-cardiac arrest

References


Andresen, Max, et al. ‘Therapeutic Hypothermia for Acute Brain Injuries’. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, vol. 23, no. 1, BioMed Central, 2015, pp. 1–7.

Bradley, Steven M., et al. ‘Temporal Trends in the Use of Therapeutic Hypothermia for Out-of-Hospital Cardiac Arrest’. JAMA Network Open, vol. 1, no. 7, American Medical Association, 2018, pp. e184511–e184511.

Dietrich, W Dalton and Bramlett, Helen M. ‘Therapeutic Hypothermia and Targeted Temperature Management in Traumatic Brain Injury: Clinical Challenges for Successful Translation’. Brain Research, vol. 1640, Elsevier, 2016, pp. 94–103.

Dietrich, W. Dalton, and Helen M. Bramlett. ‘Therapeutic Hypothermia and Targeted Temperature Management for Traumatic Brain Injury: Experimental and Clinical Experience’. Brain Circulation, vol. 3, no. 4, Wolters Kluwer--Medknow Publications, 2017, p. 186.

Gillies, Michael A., et al. ‘Therapeutic Hypothermia after Cardiac Arrest: A Retrospective Comparison of Surface and Endovascular Cooling Techniques’. Resuscitation, vol. 81, no. 9, Elsevier, 2010, pp. 1117–1122.

Haugk, Moritz, et al. ‘Relationship between Time to Target Temperature and Outcome in Patients Treated with Therapeutic Hypothermia after Cardiac Arrest’. Critical Care, vol. 15, no. 2, BioMed Central, 2011, pp. 1–8.

Howes, Daniel, et al. ‘Canadian Guidelines for the Use of Targeted Temperature Management (Therapeutic Hypothermia) after Cardiac Arrest: A Joint Statement from The Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG)’. Resuscitation, vol. 98, Elsevier, 2016, pp. 48–63.

Jackson, Travis C., and Patrick M. Kochanek. ‘A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis’. Therapeutic Hypothermia and Temperature Management, vol. 9, no. 1, Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New …, 2019, pp. 13–47.

Lascarrou, Jean-Baptiste, et al. ‘Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm’. New England Journal of Medicine, vol. 381, no. 24, Mass Medical Soc, 2019, pp. 2327–2337.

Leary, Marion, et al. ‘Pyrexia and Neurologic Outcomes after Therapeutic Hypothermia for Cardiac Arrest’. Resuscitation, vol. 84, no. 8, Elsevier, 2013, pp. 1056–1061.

Moler, Frank W., Faye S. Silverstein, Richard Holubkov, Beth S. Slomine, James R. Christensen, Vinay M. Nadkarni, Kathleen L. Meert, Brittan Browning, et al. ‘Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children’. New England Journal of Medicine, vol. 376, no. 4, Mass Medical Soc, 2017, pp. 318–329.

Moler, Frank W., Faye S. Silverstein, Richard Holubkov, Beth S. Slomine, James R. Christensen, Vinay M. Nadkarni, Kathleen L. Meert, Amy E. Clark, et al. ‘Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children’. New England Journal of Medicine, vol. 372, no. 20, Mass Medical Soc, 2015, pp. 1898–1908.

Nielsen, Niklas, et al. ‘Targeted Temperature Management at 33 C versus 36 C after Cardiac Arrest’. New England Journal of Medicine, vol. 369, no. 23, Mass Medical Soc, 2013, pp. 2197–2206.

Palmers, Pieter-Jan, et al. ‘From Therapeutic Hypothermia towards Targeted Temperature Management: A Decade of Evolution’. Anaesthesiology Intensive Therapy, vol. 47, no. 2, 2015, pp. 156–161.

Perman, Sarah M., et al. ‘Clinical Applications of Targeted Temperature Management’. Chest, vol. 145, no. 2, Elsevier, 2014, pp. 386–393.

Polderman, Kees H. ‘Is Therapeutic Hypothermia Immunosuppressive?’ Critical Care, vol. 16, BioMed Central, 2012, pp. 1–42.

Schenone, Aldo L., et al. ‘Therapeutic Hypothermia after Cardiac Arrest: A Systematic Review/Meta-Analysis Exploring the Impact of Expanded Criteria and Targeted Temperature’. Resuscitation, vol. 108, Elsevier, 2016, pp. 102–110.

Schmutzhard, Erich, et al. ‘Therapeutic Hypothermia: The Rationale’. Critical Care, vol. 16, BioMed Central, 2012, pp. 1–42.

Silverman, Michael G., and Benjamin M. Scirica. ‘Cardiac Arrest and Therapeutic Hypothermia’. Trends in Cardiovascular Medicine, vol. 26, no. 4, Elsevier, 2016, pp. 337–344.

Wang, Yechao, et al. ‘Target Temperature Management and Therapeutic Hypothermia in Sever Neuroprotection for Traumatic Brain Injury: Clinic Value and Effect on Oxidative Stress’. Medicine, vol. 102, no. 10, Wolters Kluwer Health, 2023.


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